???? ??? ??????? ? ???? ?? ???? ?? ????? ?? ?? ???? ???? ??? ???? ?? ?????? ?? ??????? ?? ???, ???????????? ???? ?? ??? ??? ?? ?????? ??? ? ?????Promethazine is metabolized via the liver to various compounds; the sulfoxides of promethazine and N-demethylpromethazine would be the predominant metabolites showing in the urine.Certain scientific studie